New Delhi Metallo-β-lactamase (blaNDM-1) in Gram-negative rods: Causing infections in children
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چکیده
منابع مشابه
New Delhi metallo-β-lactamase and OXA-48 carbapenemases in Gram-negative bacilli isolates in Libya
To the Editor Carbapenems (i.e. ertapenem, imipenem, meropenem, and doripenem) are second line antimicrobials reserved to treat serious infections, including those caused by Gramnegative bacilli (GNB) producing extended-spectrum b-lactamses (ESBLs). ESBLs mediate resistance among GNB to b-lactam drugs, including third generation cephalosporins. Emergence of carbapenemases-producing GNB (mainly ...
متن کاملNew Delhi Metallo-β-Lactamase, Ontario, Canada
To the Editor: The New Delhi metallo-β-lactamase (NDM-1) was fi rst characterized in 2009 from Kleb-siella pneumoniae and Escherichia coli isolated from a patient in Sweden who had received medical care in New Delhi, India (1). Further studies have shown broad dissemination of this β-lactamase gene (bla NDM-1) in India, Pakistan, Bangladesh, and the United Kingdom (2). Additional isolates have ...
متن کاملNDM-1 (New Delhi metallo beta lactamase-1) producing Gram-negative bacilli: Emergence & clinical implications
UNLABELLED BACKGOUND & OBJECTIVES: Resistance to carbapenems in Gram-negative bacteria conferred by NDM-1 is a global health problem. We investigated the occurrence of NDM-1 in clinical isolates of Gram-negative bacilli in a tertiary care hospital in Kashmir valley, India. METHODS Gram-negative bacilli from different clinical isolates were included in the study. Antimicrobial susceptibility w...
متن کاملNew Delhi metallo-β-lactamase-1: detection and prevention.
1240 CMAJ, August 9, 2011, 183(11) © 2011 Canadian Medical Association or its licensors The advent of New Delhi metallo-β lactamase-1 (NDM-1) as a new mechanism of microbial resistance went mostly unmarked, despite it being plasmidmediated, highly transferable and able to confer resistance to most antibiotics (with the exceptions of colistin and tigecycline). However, after the Indian subcontin...
متن کاملNosocomial Outbreak of New Delhi Metallo-β-Lactamase-1-Producing Gram-Negative Bacteria in South Africa: A Case-Control Study
OBJECTIVE New Delhi metallo-β-lactamase (NDM)-producing Gram-negative bacteria have spread globally and pose a significant public health threat. There is a need to better define risk factors and outcomes of NDM-1 clinical infection. We assessed risk factors for nosocomial infection with NDM-1-producers and associated in-hospital mortality. METHODS A matched case-control study was conducted du...
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ژورنال
عنوان ژورنال: International Journal of Infectious Diseases
سال: 2014
ISSN: 1201-9712
DOI: 10.1016/j.ijid.2014.03.636